Endocrine Abstracts

Sex steroids have complex effects: testosterone predominantly regulates trabecular and estradiol, cortical bone1. Studies in transgender individuals use insensitive technology and report conflicting effects2. We hypothesized estradiol therapy will increase cortical volumetric bone mineral density (vBMD) in male-to-female (MtF) individuals and testosterone therapy will increase trabecular vBMD in female-to-male (FtM) individuals.Aims...

Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) leads to a global loss of lean mass. ADT leads to sexual dysfunction and a selective loss of leg muscle function, however individual muscle volumes have never been evaluated. We aimed to assess in men undergoing ADT, the muscle volumes of levator ani, which in mice is androgen-responsive, and of lower-limb muscles.Methods: We conducted a prospective case-control study involving 34 m...

Introduction: Contrast-induced nephropathy (CIN) is an important cause of acute kidney injury (AKI) in inpatients. However, the prevalence and predisposing factors for CIN remain poorly documented. The aim of this study was to investigate the association between CIN, kidney function and diabetic status in inpatients.Methods: We identified inpatients who received IV contrast prior to a computed tomography (CT) scan between July 2012 to March 2018 at Austi...